发明申请
- 专利标题: 7-AMINOFUROPYRIDINE DERIVATIVES
- 专利标题(中): 7-氨基脲衍生物
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申请号: US13025281申请日: 2011-02-11
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公开(公告)号: US20120046267A1公开(公告)日: 2012-02-23
- 发明人: Keith R. Hornberger , Dan M. Berger , Xin Chen , Andrew P. Crew , Hanqing Dong , Andrew Kleinberg , An-Hu Li , Lifu Ma , Mark J. Mulvihill , Bijoy Panicker , Kam W. Siu , Arno G. Steinig , James G. Tarrant , Jing Wang , Qinghua Weng , Rajaram Sangem , Ramesh C. Gupta
- 申请人: Keith R. Hornberger , Dan M. Berger , Xin Chen , Andrew P. Crew , Hanqing Dong , Andrew Kleinberg , An-Hu Li , Lifu Ma , Mark J. Mulvihill , Bijoy Panicker , Kam W. Siu , Arno G. Steinig , James G. Tarrant , Jing Wang , Qinghua Weng , Rajaram Sangem , Ramesh C. Gupta
- 专利权人: OSI PHARMACEUTICALS, INC.
- 当前专利权人: OSI PHARMACEUTICALS, INC.
- 主分类号: A61K31/4355
- IPC分类号: A61K31/4355 ; A61K31/4545 ; A61K31/4725 ; A61K31/4709 ; A61K31/5377 ; C07D495/04 ; A61K31/4365 ; A61K31/519 ; A61K31/5025 ; C07D513/04 ; A61K31/437 ; C07D487/04 ; A61K31/4985 ; A61K31/502 ; C12N9/99 ; A61P35/00 ; A61P29/00 ; C07D491/048
摘要:
Compounds of Formula 1, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by TAK1 or for which an appropriate TAK1 inhibitor is effective. This Abstract is not limiting of the invention.
公开/授权文献
- US08378104B2 7-aminofuropyridine derivatives 公开/授权日:2013-02-19