发明申请
- 专利标题： Hydrazonamide Compounds That Modulate Hsp90 Activity
- 专利标题（中）： 调节Hsp90活性的肼腙化合物
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申请号： US13001255申请日： 2009-06-26
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公开(公告)号： US20120046288A1公开(公告)日： 2012-02-23
- 发明人: Joseph A. Burlison , Dinesh U. Chimmanamada , Weiwen Ying , Shijie Zhang , David James
- 申请人： Joseph A. Burlison , Dinesh U. Chimmanamada , Weiwen Ying , Shijie Zhang , David James
- 专利权人： Synta Pharmacueticals Corp.
- 当前专利权人： Synta Pharmacueticals Corp.
- 国际申请： PCT/US09/03825 WO 20090626
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D295/155 ; C07D317/66 ; A61P35/00 ; C07D405/12 ; A61K31/535 ; A61K31/36 ; A61K31/4525 ; C07D413/04 ; C07D317/58
摘要：
The present invention relates to substituted hydrazonamide compounds. The invention further relates to methods of inhibiting the activity of Hsρ90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted hydrazonamide compound of the invention, or a pharmaceutical composition comprising such a compound.
公开/授权文献
- US08648071B2 Hydrazonamide compounds that modulate Hsp90 activity 公开/授权日：2014-02-11