发明申请
US20120070409A1 TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR
审中-公开
四氢呋喃杂交化合物及其作为HCV聚合酶抑制剂的用途
- 专利标题： TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR
- 专利标题（中）： 四氢呋喃杂交化合物及其作为HCV聚合酶抑制剂的用途
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申请号： US13020621申请日： 2011-02-03
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公开(公告)号： US20120070409A1公开(公告)日： 2012-03-22
- 发明人: Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
- 申请人： Takahiro Oka , Kazutaka Ikegashira , Shintaro Hirashima , Hiroshi Yamanaka , Satoru Noji , Yasushi Niwa , Yoko Matsumoto , Toshihiro Sato , Izuru Ando , Yukihiro Nomura
- 申请人地址： JP Tokyo
- 专利权人： Japan Tobacco Inc.
- 当前专利权人： Japan Tobacco Inc.
- 当前专利权人地址： JP Tokyo
- 优先权： JP48815/2004 20040224; JP169190/2004 20040607; JP296390/2004 20041008
- 主分类号： A61K31/553
- IPC分类号： A61K31/553 ; C07D487/04 ; C07D498/04 ; C07D513/04 ; A61K31/5365 ; A61K31/55 ; A61K31/407 ; A61K31/542 ; A61P1/16 ; A61K38/21 ; A61P31/14 ; A61K31/554 ; C07D498/14 ; C07D471/14 ; C07D471/04 ; A61K31/4745 ; C07D519/00 ; A61K31/5517
摘要：
The present invention relates to a tetracyclic fused heterocyclic compound represented by the following formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable a salt thereof, and a hepatitis C virus (HCV) polymerase inhibitor and a therapeutic agent for hepatitis C containing this compound. The compound of the present invention shows an anti-HCV activity based on the HCV polymerase inhibitory activity, and useful as an agent for the prophylaxis or treatment of hepatitis C.
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