发明申请
- 专利标题： TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
- 专利标题（中）： 调节HSP90活性的三唑化合物
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申请号： US13333191申请日： 2011-12-21
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公开(公告)号： US20120101072A1公开(公告)日： 2012-04-26
- 发明人: Joseph A. Burlison , Shijie Zhang , Weiwen Ying , Dinesh U. Chimmanamada , Minghu Song , Junghyun Chae , Stefan M. Schweizer
- 申请人： Joseph A. Burlison , Shijie Zhang , Weiwen Ying , Dinesh U. Chimmanamada , Minghu Song , Junghyun Chae , Stefan M. Schweizer
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 主分类号： A61K31/4196
- IPC分类号： A61K31/4196 ; C07D413/14 ; C07D417/14 ; C07D405/10 ; A61P35/00 ; A61K31/496 ; A61K31/5377 ; A61K31/541 ; A61K31/454 ; A61K31/635 ; C07D403/10 ; C07D413/10
摘要：
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound.
公开/授权文献
- US08486932B2 Triazole compounds that modulate Hsp90 activity 公开/授权日：2013-07-16
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