发明申请
US20120122216A1 OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS
有权
用于调节小型非编码RNAs的低分子化合物和组合物
- 专利标题: OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAS
- 专利标题(中): 用于调节小型非编码RNAs的低分子化合物和组合物
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申请号: US13359271申请日: 2012-01-26
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公开(公告)号: US20120122216A1公开(公告)日: 2012-05-17
- 发明人: Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta
- 申请人: Christine Esau , Bridget Lollo , C. Frank Bennett , Susan M. Freier , Richard H. Griffey , Brenda F. Baker , Timothy A. Vickers , Eric G. Marcusson , Erich Koller , Eric E. Swayze , Ravi Jain , Balkrishen Bhat , Eigen Peralta
- 申请人地址: US CA Carlsbad
- 专利权人: REGULUS THERAPEUTICS, INC.
- 当前专利权人: REGULUS THERAPEUTICS, INC.
- 当前专利权人地址: US CA Carlsbad
- 主分类号: C12N5/071
- IPC分类号: C12N5/071
摘要:
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric compounds, targeted to small non-coding RNAs. Methods of using these compounds for modulation of small non-coding RNAs as well as downstream targets of these RNAs and for diagnosis and treatment of disease associated with small non-coding RNAs are also provided.