发明申请
US20120136016A1 4, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS
有权
作为因子IXA抑制剂的4,5,6-取代的吡嗪衍生物
- 专利标题： 4, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS
- 专利标题（中）： 作为因子IXA抑制剂的4,5,6-取代的吡嗪衍生物
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申请号： US13388628申请日： 2010-08-03
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公开(公告)号： US20120136016A1公开(公告)日： 2012-05-31
- 发明人: Mariappan V. Chelliah , Samuel Chackalamannil , William J. Greenlee , Keith Eagen , Zhuyan Guo , Martin C. Clasby , Yan Xia , Charles L. Jayne , Michael Dwyer , Kartick M. Keertikar , Tin-Yau Chan , Li Wang
- 申请人： Mariappan V. Chelliah , Samuel Chackalamannil , William J. Greenlee , Keith Eagen , Zhuyan Guo , Martin C. Clasby , Yan Xia , Charles L. Jayne , Michael Dwyer , Kartick M. Keertikar , Tin-Yau Chan , Li Wang
- 国际申请： PCT/US10/44208 WO 20100803
- 主分类号： A61K31/505
- IPC分类号： A61K31/505 ; C07D403/04 ; A61P7/02 ; C07D403/12 ; C07D401/12 ; C07D239/47 ; C07D239/60
摘要：
The present invention relates to novel heterocyclic compounds of Formulae (I): (Chemical formula should be inserted here as it appears on abstract in paper form) Formula (I) as disclosed herein, or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and methods for using said compounds for treating or preventing a thromboembolic disorder.
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