发明申请
- 专利标题： MODULATION OF TRANSTHYRETIN EXPRESSION
- 专利标题（中）： TRANSTHYRETIN表达调控
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申请号： US13357481申请日： 2012-01-24
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公开(公告)号： US20120149109A1公开(公告)日： 2012-06-14
- 发明人: Vickie L. Brown-Driver , Ravi Jain
- 申请人： Vickie L. Brown-Driver , Ravi Jain
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 主分类号： C12N5/071
- IPC分类号： C12N5/071
摘要：
Compounds, compositions and methods are provided for modulating the expression of transthyretin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding transthyretin. Methods of using these compounds for modulation of transthyretin expression and for diagnosis and treatment of diseases and conditions associated with expression of transthyretin are provided.
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