发明申请
- 专利标题： QUINOLINE DERIVATIVES AS PI3 KINASE INHIBITORS
- 专利标题（中）： 喹啉衍生物作为PI3激酶抑制剂
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申请号： US13411887申请日： 2012-03-05
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公开(公告)号： US20120165321A1公开(公告)日： 2012-06-28
- 发明人: Nicholas D. Adams , Joelle Lorraine Burgess , Michael Gerrard Darcy , Carla A. Donatelli , Steven David Knight , Kenneth Allen Newlander , Lance Ridgers , Martha A. Sarpong , Stanley J. Schmidt
- 申请人： Nicholas D. Adams , Joelle Lorraine Burgess , Michael Gerrard Darcy , Carla A. Donatelli , Steven David Knight , Kenneth Allen Newlander , Lance Ridgers , Martha A. Sarpong , Stanley J. Schmidt
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; C07D413/14 ; A61K31/5377 ; A61K31/496 ; C07D471/04 ; C07D498/04 ; A61K31/5383 ; C07D417/14 ; A61K31/549 ; A61P37/00 ; A61P29/00 ; A61P9/00 ; A61P25/28 ; A61P37/08 ; A61P11/06 ; A61P1/18 ; A61P13/12 ; A61P7/02 ; A61P35/00 ; A61P15/08 ; A61P37/06 ; A61P11/00 ; A61P17/06 ; A61P19/04 ; A61P1/00 ; A61P25/14 ; A61P25/00 ; A61P9/10 ; A61P9/08 ; A61P21/00 ; A61P35/04 ; A61P31/04 ; A61P31/12 ; A61P35/02 ; C07D401/14
摘要：
Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
公开/授权文献
- US08633187B2 Quinoline derivatives as PI3 kinase inhibitors 公开/授权日：2014-01-21