发明申请
US20120172329A1 PHYTOCHEMICAL COMPOSITIONS INCLUDING XANTHONES FOR ANTI-INFLAMMATORY, ANTI-CYTOKINE STORM, AND OTHER USES
审中-公开
生物化学组合物，包括用于抗炎，抗细菌因子和其他用途的XANTHONES
- 专利标题： PHYTOCHEMICAL COMPOSITIONS INCLUDING XANTHONES FOR ANTI-INFLAMMATORY, ANTI-CYTOKINE STORM, AND OTHER USES
- 专利标题（中）： 生物化学组合物，包括用于抗炎，抗细菌因子和其他用途的XANTHONES
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申请号： US13496191申请日： 2009-09-14
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公开(公告)号： US20120172329A1公开(公告)日： 2012-07-05
- 发明人: Prachya Kongtawelert
- 申请人： Prachya Kongtawelert
- 申请人地址： TH District,, Chiang Mai ,
- 专利权人： Thailand Excellence Center for Tissue Engineering
- 当前专利权人： Thailand Excellence Center for Tissue Engineering
- 当前专利权人地址： TH District,, Chiang Mai ,
- 国际申请： PCT/SG2009/000339 WO 20090914
- 主分类号： A61K31/352
- IPC分类号： A61K31/352 ; A61K31/7008 ; A61P31/16 ; A61P29/00 ; A61P31/12 ; A61K31/616 ; A61K31/737
摘要：
A composition (e.g., a phytochemical composition) including a predetermined concentration of xanthones, and in certain embodiments predetermined concentrations of both xanthones and sesamin. The composition facilitates at least one of decreasing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, enhancing a connective tissue anti- degeneration effect, and inhibiting viral neuraminidase (e.g. neuraminidase of an influenza A virus). The composition can further decrease at least one of gene expression and release of pro-inflammatory cytokines. The phytochemical composition can increase at least one of gene expression and release of anti-inflammatory cytokines. The phytochemical composition provides at least one of an anti-inflammatory, an anti-viral (e.g., anti-influenza), and a connective tissue anti-degradation effect in a living organism. A use of xanthones for manufacturing phytochemical compositions that include predetermined concentrations of xanthones is also provided. A use of xanthones in combination with sesamin for manufacturing phytochemical compositions that include predetermined concentrations of both xanthones and sesamin is additionally provided.
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