公开(公告)号：US20120172329A1

公开(公告)日：2012-07-05

申请号：US13496191

申请日：2009-09-14

申请人： Prachya Kongtawelert

发明人： Prachya Kongtawelert

IPC分类号： A61K31/352 ,  A61K31/7008 ,  A61P31/16 ,  A61P29/00 ,  A61P31/12 ,  A61K31/616 ,  A61K31/737

CPC分类号： A61K31/352 ,  A23L33/105 ,  A61K2300/00

摘要： A composition (e.g., a phytochemical composition) including a predetermined concentration of xanthones, and in certain embodiments predetermined concentrations of both xanthones and sesamin. The composition facilitates at least one of decreasing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, enhancing a connective tissue anti- degeneration effect, and inhibiting viral neuraminidase (e.g. neuraminidase of an influenza A virus). The composition can further decrease at least one of gene expression and release of pro-inflammatory cytokines. The phytochemical composition can increase at least one of gene expression and release of anti-inflammatory cytokines. The phytochemical composition provides at least one of an anti-inflammatory, an anti-viral (e.g., anti-influenza), and a connective tissue anti-degradation effect in a living organism. A use of xanthones for manufacturing phytochemical compositions that include predetermined concentrations of xanthones is also provided. A use of xanthones in combination with sesamin for manufacturing phytochemical compositions that include predetermined concentrations of both xanthones and sesamin is additionally provided.

摘要翻译： 包括预定浓度的呫吨酮的组合物（例如，植物化学组合物），在某些实施方案中，预定浓度的呫吨酮和芝麻素。 组合物促进减少促炎细胞因子，增加抗炎细胞因子，增强结缔组织抗变性作用和抑制病毒神经氨酸酶（例如甲型流感病毒的神经氨酸酶）中的至少一种。 组合物可以进一步降低基因表达和促炎细胞因子释放中的至少一种。 植物化学成分可以增加抗炎细胞因子的基因表达和释放中的至少一种。 植物化学组合物在活体中提供抗炎，抗病毒（例如抗流行性感冒）和结缔组织抗降解作用中的至少一种。 还提供了使用呫吨酮制备包含预定浓度的呫吨酮的植物化学组合物。 另外提供了将呫吨酮与芝麻素组合用于制备包括预定浓度的呫吨酮和芝麻素的植物化学成分的用途。