发明申请
- 专利标题： Chimaeric Protein
- 专利标题（中）： 嵌合蛋白
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申请号： US13382119申请日： 2010-07-05
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公开(公告)号： US20120177675A1公开(公告)日： 2012-07-12
- 发明人: Paul Britton , Erica Bickerton , Maria Armesto
- 申请人： Paul Britton , Erica Bickerton , Maria Armesto
- 申请人地址： GB Pirbright
- 专利权人： INSTITUTE FOR ANIMAL HEALTH
- 当前专利权人： INSTITUTE FOR ANIMAL HEALTH
- 当前专利权人地址： GB Pirbright
- 优先权： GBGB0911794.6 20090707
- 国际申请： PCT/GB10/01293 WO 20100705
- 主分类号： A61K39/215
- IPC分类号： A61K39/215 ; C12N15/50 ; A61P31/14 ; C12N5/071 ; C12N15/85 ; C12N7/01 ; C12N7/02 ; C07K7/06 ; A61P31/16
摘要：
The present invention provides a chimaeric coronavirus S protein which is based on an S protein from a coronavirus strain with restricted tissue tropism, but which comprises at least part of the S2 subunit from a coronavirus strain with extended tissue tropism, such that a virus comprising the chimaeric S protein has extended tissue tropism. The present invention also provides a virus comprising such a chimaeric S protein.
公开/授权文献
- US08828407B2 Chimaeric protein 公开/授权日：2014-09-09
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