发明申请
US20120184741A1 SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[5-[2-(1-HYDROXY-METHYL-ETHYL)PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA
有权
γ-乙基-3- [5- [2-（1-羟基 - 甲基）乙基]嘧啶-5-基] -7-（四氢呋喃-2-基）-1H-苯并咪唑的固体形式 -2-YL]尿素
![SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[5-[2-(1-HYDROXY-METHYL-ETHYL)PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA](/docs/US/2012-07-19/US20120184741A1/abs.jpg.600x600.jpg)
- 专利标题： SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[5-[2-(1-HYDROXY-METHYL-ETHYL)PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA
- 专利标题（中）： γ-乙基-3- [5- [2-（1-羟基 - 甲基）乙基]嘧啶-5-基] -7-（四氢呋喃-2-基）-1H-苯并咪唑的固体形式 -2-YL]尿素
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申请号： US13349845申请日： 2012-01-13
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公开(公告)号： US20120184741A1公开(公告)日： 2012-07-19
- 发明人: Dean Shannon , Brian Luisi , Yusheng Liao , Mariusz Krawiec
- 申请人： Dean Shannon , Brian Luisi , Yusheng Liao , Mariusz Krawiec
- 申请人地址： US MA Cambridge
- 专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址： US MA Cambridge
- 主分类号： C07D405/14
- IPC分类号： C07D405/14
![SOLID FORMS OF GYRASE INHIBITOR (R)-1-ETHYL-3-[5-[2-(1-HYDROXY-METHYL-ETHYL)PYRIMIDIN-5-YL]-7-(TETRAHYDROFURAN-2-YL)-1H-BENZIMIDAZOL-2-YL]UREA](/abs-image/US/2012/07/19/US20120184741A1/abs.jpg.150x150.jpg)
摘要：
The present application is directed to solid forms of compounds of formula (I): and pharmaceutically acceptable salts thereof, that inhibit bacterial gyrase and/or Topo IV and pharmaceutical compositions comprising said compounds and salts. These compounds and salts are useful in treating bacterial infection.
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