Invention Application
US20120190738A1 INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO)
有权
磷脂酰肌醇三激酶（PI3）和氧化氮（NO）的诱导剂的抑制剂
- Patent Title: INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO)
- Patent Title (中): 磷脂酰肌醇三激酶（PI3）和氧化氮（NO）的诱导剂的抑制剂
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Application No.: US13144263Application Date: 2010-01-12
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Publication No.: US20120190738A1Publication Date: 2012-07-26
- Inventor: Santu Bandyopadhyay , Bikas Chandra Pal , Jaisankar Parasuraman , Siddhartha Roy , Jayashree Bagchi Chakrabotry , Indrani Choudhury Mukherjee , Sanjit Kumar Mahato , Aditya Konar , Srabanti Rakshit , Labanya Mandal , Dipyaman Ganguly , Kausik Paul , Anirban Manna , Jayaraman Vinayagam , Churala Pal
- Applicant: Santu Bandyopadhyay , Bikas Chandra Pal , Jaisankar Parasuraman , Siddhartha Roy , Jayashree Bagchi Chakrabotry , Indrani Choudhury Mukherjee , Sanjit Kumar Mahato , Aditya Konar , Srabanti Rakshit , Labanya Mandal , Dipyaman Ganguly , Kausik Paul , Anirban Manna , Jayaraman Vinayagam , Churala Pal
- Priority: IN44/DEL/2009 20090112
- International Application: PCT/IB2010/000040 WO 20100112
- Main IPC: A61K31/36
- IPC: A61K31/36 ; A61K31/225 ; C07C215/54 ; A61K31/138 ; C07C255/33 ; A61P35/02 ; A61K31/15 ; C07D317/50 ; C07C39/10 ; A61K31/05 ; A61P35/00 ; C07C69/353 ; A61K31/277
Abstract:
The present invention relates to compounds of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.
Public/Granted literature
- US09290473B2 Inhibitors of phosphatidylinositol-3-kinase (PI3) and inducers of nitric oxide (NO) Public/Granted day:2016-03-22
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