Invention Application
- Patent Title: NOVEL GUANOSINE-RICH MODIFIED OLIGONUCLEOTIDES AND ANTIPROLIFERATIVE ACTIVITY THEREOF
- Patent Title (中): 新型冠心病修饰寡核苷酸及其抗增殖活性
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Application No.: US13381326Application Date: 2010-06-29
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Publication No.: US20120202981A1Publication Date: 2012-08-09
- Inventor: Soo Jin Lee , Sung Hwan Moon
- Applicant: Soo Jin Lee , Sung Hwan Moon
- Applicant Address: KR Suwon-si Gyeonggi-do
- Assignee: APTABIO THERAPEUTICS INC.
- Current Assignee: APTABIO THERAPEUTICS INC.
- Current Assignee Address: KR Suwon-si Gyeonggi-do
- Priority: KR10-2009-0058498 20090629; KR10-2010-0051202 20100531
- International Application: PCT/KR2010/004202 WO 20100629
- Main IPC: C07H21/00
- IPC: C07H21/00
Abstract:
The present invention relates to a novel modified oligonucleotide comprising at least one guanosine molecule and a modified nucleic acid with therapeutic efficacies. The present invention also relates to a pharmaceutical composition having cell apoptotic activity against cancer cells for preventing or treating cancer comprising a guanosine-rich modified oligonucleotide with at least one therapeutically effective modified nucleic acid (N), or its pharmaceutically acceptable salt as active ingredient.
Public/Granted literature
- US09056886B2 Guanosine-rich modified oligonucleotides and antiproliferative activity thereof Public/Granted day:2015-06-16
Information query
