发明申请
![3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINES](/docs/US/2012-08-23/US20120214806A1/abs.jpg.600x600.jpg)
- 专利标题： 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINES
- 专利标题（中）： 3-氨基-5-苯基-5,6-二氢-2H- [1,4]氧化物
-
申请号： US13460905申请日： 2012-05-01
-
公开(公告)号： US20120214806A1公开(公告)日： 2012-08-23
- 发明人: Matteo Andreini , David Banner , Emanuele Gabellieri , Wolfgang Guba , Hans Hilpert , Harald Mauser , Alexander V. Mayweg , Robert Narquizian , Eoin Power , Mark Rogers-Evans , Massimiliano Travagli , Michela Valacchi , Thomas Woltering , Wolfgang Wostl
- 申请人： Matteo Andreini , David Banner , Emanuele Gabellieri , Wolfgang Guba , Hans Hilpert , Harald Mauser , Alexander V. Mayweg , Robert Narquizian , Eoin Power , Mark Rogers-Evans , Massimiliano Travagli , Michela Valacchi , Thomas Woltering , Wolfgang Wostl
- 优先权： EP09168132.0 20090819
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D265/30 ; A61K31/5375 ; C07D471/04 ; C07D417/12 ; C07D413/14 ; A61P3/10 ; A61P25/28 ; A61P3/00 ; A61P7/02 ; A61P37/00 ; A61P29/00 ; A61P35/00 ; A61P9/10 ; A61P25/00 ; A61P17/00 ; A61P1/00 ; A61P5/16 ; A61P19/04 ; A61P19/02 ; C07D265/32 ; C07D413/12
![3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINES](/abs-image/US/2012/08/23/US20120214806A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates to 3-Amino-5-phenyl-5,6-dihydro-2H-[1,4]oxazines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
信息查询
IPC分类:
