发明申请
- 专利标题: TRICYCLIC INHIBITORS OF KINASES
- 专利标题(中): 金刚石三元抑制剂
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申请号: US13406937申请日: 2012-02-28
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公开(公告)号: US20120220572A1公开(公告)日: 2012-08-30
- 发明人: Yunsong Tong , Thomas D. Penning , Alan S. Florjancic , Julie Miyashiro , Keith W. Woods
- 申请人: Yunsong Tong , Thomas D. Penning , Alan S. Florjancic , Julie Miyashiro , Keith W. Woods
- 申请人地址: US IL Abbott Park
- 专利权人: ABBOTT LABORATORIES
- 当前专利权人: ABBOTT LABORATORIES
- 当前专利权人地址: US IL Abbott Park
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K31/5377 ; A61K31/538 ; A61P35/00 ; A61K31/55 ; C07D471/04 ; C07D513/04 ; A61K31/541 ; C07D487/14 ; A61K31/551
摘要:
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein X, Y, Z, R3 and R4 are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as wee-1 and methods of treating diseases such as cancer.
公开/授权文献
- US08710065B2 Tricyclic inhibitors of kinases 公开/授权日:2014-04-29