发明申请
US20120252681A1 EVOLUTION OF WHOLE CELLS AND ORGANISMS BY RECURSIVE SEQUENCE RECOMBINATION
有权
通过重新序列重组实现全细胞和有机体的发育
- 专利标题： EVOLUTION OF WHOLE CELLS AND ORGANISMS BY RECURSIVE SEQUENCE RECOMBINATION
- 专利标题（中）： 通过重新序列重组实现全细胞和有机体的发育
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申请号： US13310332申请日： 2011-12-02
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公开(公告)号： US20120252681A1公开(公告)日： 2012-10-04
- 发明人: Stephen del Cardayre , Matthew Tobin , Willem P.C. Stemmer , Jon E. Ness , Jeremy Minshull , Phillip Patten , Venkiteswaran Subramanian , Linda A. Castle , Claus M. Krebber , Steven H. Bass , Ying-Xin Zhang , Tony Cox , Gjalt Huisman , Ling Yuan , Joseph A. Affholter
- 申请人： Stephen del Cardayre , Matthew Tobin , Willem P.C. Stemmer , Jon E. Ness , Jeremy Minshull , Phillip Patten , Venkiteswaran Subramanian , Linda A. Castle , Claus M. Krebber , Steven H. Bass , Ying-Xin Zhang , Tony Cox , Gjalt Huisman , Ling Yuan , Joseph A. Affholter
- 申请人地址： US CA Redwood City
- 专利权人： CODEXIS MAYFLOWER HOLDINGS, LLC
- 当前专利权人： CODEXIS MAYFLOWER HOLDINGS, LLC
- 当前专利权人地址： US CA Redwood City
- 优先权： USPCT/US1998/00852 19980116
- 主分类号： C40B10/00
- IPC分类号： C40B10/00
摘要：
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
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