发明申请
US20120277424A1 2,7-SUBSTITUTED THIENO[3,2-D] PYRIMIDINE COMPOUNDS AS PROTEIN KINASE INHIBITORS
失效
2,7-取代的噻吩并[3,2-D]吡啶化合物作为蛋白激酶抑制剂
- 专利标题: 2,7-SUBSTITUTED THIENO[3,2-D] PYRIMIDINE COMPOUNDS AS PROTEIN KINASE INHIBITORS
- 专利标题(中): 2,7-取代的噻吩并[3,2-D]吡啶化合物作为蛋白激酶抑制剂
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申请号: US13503125申请日: 2010-10-15
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公开(公告)号: US20120277424A1公开(公告)日: 2012-11-01
- 发明人: Tae Bo Sim , Hwan Geun Choi , Jung Mi Hah , Young Jin Ham , Eun Jin Jun , Jung Hun Lee , Hwan Kim
- 申请人: Tae Bo Sim , Hwan Geun Choi , Jung Mi Hah , Young Jin Ham , Eun Jin Jun , Jung Hun Lee , Hwan Kim
- 申请人地址: KR Seoul
- 专利权人: Korea Institute of Science and Technology
- 当前专利权人: Korea Institute of Science and Technology
- 当前专利权人地址: KR Seoul
- 优先权: KR10-2009-0100867 20091022
- 国际申请: PCT/KR2010/007093 WO 20101015
- 主分类号: C07D495/04
- IPC分类号: C07D495/04
摘要:
Disclosed are a 2,7-substituted thieno[3,2-d]pyrimidine compound having a protein kinase inhibition activity, a pharmaceutically acceptable salt, and a pharmaceutical composition for prevention and treatment of diseases caused by abnormal cell growth comprising the compound as an effective ingredient.Since the novel 2,7-substituted thieno[3,2-d]pyrimidine compound exhibits superior inhibition activity against various protein kinases involved in growth factor signal transduction, it is useful as an agent for preventing or treating diseases caused by abnormal cell growth.
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