发明申请
- 专利标题： 9-SUBSTITUTED MINOCYCLINE COMPOUNDS
- 专利标题（中）： 9-取代的咪唑啉化合物
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申请号： US13547870申请日： 2012-07-12
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公开(公告)号： US20120283201A1公开(公告)日： 2012-11-08
- 发明人: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Y. Ismail , Todd Bowser , Jimmy Dumornay , Glen Rennie , Gui Liu , Darrell J. Koza , Paul Sheahan , Karen Stapleton , Paul Hawkins , Beena Bhalie , Atul K. Verma , Laura Honeyman , Tadeusz Warchol , David Messersmith
- 申请人： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Y. Ismail , Todd Bowser , Jimmy Dumornay , Glen Rennie , Gui Liu , Darrell J. Koza , Paul Sheahan , Karen Stapleton , Paul Hawkins , Beena Bhalie , Atul K. Verma , Laura Honeyman , Tadeusz Warchol , David Messersmith
- 申请人地址： US MA Medford US MA Boston
- 专利权人： Trustees of Tufts College,Paratek Pharmaceuticals, Inc.
- 当前专利权人： Trustees of Tufts College,Paratek Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Medford US MA Boston
- 主分类号： A61K31/65
- IPC分类号： A61K31/65 ; C07C275/40 ; C07C271/30 ; C07D307/81 ; C07D333/24 ; C07D317/60 ; C07F9/40 ; A61K31/662 ; C07C311/21 ; C07C255/60 ; C07F7/10 ; A61K31/695 ; C07D295/155 ; C07C275/54 ; C07C335/20 ; C07C311/05 ; C07D213/56 ; C07C279/18 ; C07H15/203 ; A61K31/7034 ; A61P31/04 ; A61P35/00 ; C07D213/64 ; C07C237/26
摘要：
The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
公开/授权文献
- US09090541B2 9-substituted minocycline compounds 公开/授权日：2015-07-28
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