- 专利标题： COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS
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申请号： US13558886申请日： 2012-07-26
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公开(公告)号： US20120289483A1公开(公告)日： 2012-11-15
- 发明人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人： Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人地址： US MA Lexington
- 专利权人： SYNTA PHARMACEUTICALS CORPORATION
- 当前专利权人： SYNTA PHARMACEUTICALS CORPORATION
- 当前专利权人地址： US MA Lexington
- 主分类号： A61K31/42
- IPC分类号： A61K31/42 ; C07D261/08 ; C07F9/653 ; C07D413/04 ; A61P35/00 ; A61K31/4439 ; A61K31/4725 ; A61K31/4709 ; A61K31/422 ; A61K31/675 ; C07D413/10
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US08598366B2 Compounds for the treatment of proliferative disorders 公开/授权日：2013-12-03
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