发明申请
US20120289546A1 MONOHYDROCHLORIDE SALT OF 1-[3-[3-(4-CHLOROPHENYL) PROPOXY]PROPYL]-PIPERIDINE
有权
1- [3- [3-(4-氯苯基)丙氧基]丙氧基]丙酸的单盐酸盐
- 专利标题: MONOHYDROCHLORIDE SALT OF 1-[3-[3-(4-CHLOROPHENYL) PROPOXY]PROPYL]-PIPERIDINE
- 专利标题(中): 1- [3- [3-(4-氯苯基)丙氧基]丙氧基]丙酸的单盐酸盐
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申请号: US13491229申请日: 2012-06-07
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公开(公告)号: US20120289546A1公开(公告)日: 2012-11-15
- 发明人: Manuel RAGA , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
- 申请人: Manuel RAGA , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
- 优先权: EP05100942.1 20050210
- 主分类号: A61K31/4453
- IPC分类号: A61K31/4453 ; A61P25/00
摘要:
A method is provided for the treatment of sleep apnea and other conditions wherein an effective amount of crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride of formula (I): optionally comprising water up to 6%, and having an X-ray diffractogram that comprises characteristic peaks (2θ) at 11.2°, 19.9°, 20.7° and 34.1°±0.2° is administered to a patient in need thereof.
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