发明申请
US20120295910A1 New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists
审中-公开
新的苯基氨磺酰苯甲酰胺衍生物作为缓激肽拮抗剂
- 专利标题： New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists
- 专利标题（中）： 新的苯基氨磺酰苯甲酰胺衍生物作为缓激肽拮抗剂
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申请号： US13564360申请日： 2012-08-01
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公开(公告)号： US20120295910A1公开(公告)日： 2012-11-22
- 发明人: Gyula Beke , Eva Bozo , Sandor Farkas , Katalin Hornok , Gyorgy Keseru , Eva Schmidt , Eva Szentirmay , Istvan Vago , Monika Vastag
- 申请人： Gyula Beke , Eva Bozo , Sandor Farkas , Katalin Hornok , Gyorgy Keseru , Eva Schmidt , Eva Szentirmay , Istvan Vago , Monika Vastag
- 优先权： HUP0600809 20061027
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; A61K31/4965 ; A61K31/4545 ; A61K31/445 ; A61K31/4164 ; C07D207/50 ; C07D265/30 ; C07D401/02 ; C07D241/04 ; C07D401/04 ; C07D211/56 ; C07D233/88 ; A61K31/497 ; A61K31/40
摘要：
The present invention relates to new sulfonamide derivatives of formula (I), wherein R1-R8 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these same compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
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