A method for producing a reaction product containing 99mTC may include providing 100Mo-metal targets to be irradiated, irradiating the 100Mo-metal target with a proton stream having an energy for the induction of a 100Mo(p, 2n)99mTC core reaction, heating the 100Mo-metal target to over 300° C., recovering incurred 99mTc in a sublimation-extraction process with the aid of oxygen gas which is conducted over the 100 Mo-metal target forming 99mTc-Technetium oxide. Further, a device for producing the reaction product containing 99mTc may include a 100Mo metal target, an acceleration unit for providing a proton stream, which can be directed to the 100Mo-Metal target, such that a 100Mo(p, 2n)99mTC core reaction is induced upon irradiation of the 100Mo-metal target by the proton stream, a gas supply line for conducting oxygen gas onto the irradiated 100Mo-metal target to form 99mTC-Technetium oxide, and a gas discharge line to discharge the sublimated 99mTC-Technetium oxide.