Invention Application
US20120309963A1 5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS
有权
5-氰基-4-(吡咯并[2,3B]吡啶-3-基) - 吡啶衍生物,用作蛋白激酶抑制剂
- Patent Title: 5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS
- Patent Title (中): 5-氰基-4-(吡咯并[2,3B]吡啶-3-基) - 吡啶衍生物,用作蛋白激酶抑制剂
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Application No.: US13477663Application Date: 2012-05-22
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Publication No.: US20120309963A1Publication Date: 2012-12-06
- Inventor: Michael Mortimore , Stephen Clinton Young , Simon Robert Lorrie Everitt , Ronald Knegtel , Joanne Louise Pinder , Alistair Peter Rutherford , Steven Durrant , Guy Brenchley , Jean-Damien Charrier , Michael O'Donnell
- Applicant: Michael Mortimore , Stephen Clinton Young , Simon Robert Lorrie Everitt , Ronald Knegtel , Joanne Louise Pinder , Alistair Peter Rutherford , Steven Durrant , Guy Brenchley , Jean-Damien Charrier , Michael O'Donnell
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Main IPC: C07D471/04
- IPC: C07D471/04
![5-CYANO-4- (PYRROLO [2,3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS](/abs-image/US/2012/12/06/US20120309963A1/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
Public/Granted literature
- US08530489B2 5-cyano-4-(pyrrolo [2,3B] pyridine-3-yl)-pyrimidine derivatives useful as protein kinase inhibitors Public/Granted day:2013-09-10
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