Invention Application
US20120322684A1 G-CSF PROTEIN HAVING A DELETION OF AN AMINO ACID SEQUENCE CORRESPONDING TO EXON 3 FOR USE AS A DIAGNOSTIC CANCER MARKER
审中-公开
具有相关性的氨基酸序列的G-CSF蛋白3用作诊断性癌症标记
- Patent Title: G-CSF PROTEIN HAVING A DELETION OF AN AMINO ACID SEQUENCE CORRESPONDING TO EXON 3 FOR USE AS A DIAGNOSTIC CANCER MARKER
- Patent Title (中): 具有相关性的氨基酸序列的G-CSF蛋白3用作诊断性癌症标记
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Application No.: US13546972Application Date: 2012-07-11
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Publication No.: US20120322684A1Publication Date: 2012-12-20
- Inventor: Sang Yup Lee , Nae Choon Yoo , So Young Yoo , Hyun Cheol Chung , Ki Chang Keum , Won Min Yoo , Ki Jun Jeong
- Applicant: Sang Yup Lee , Nae Choon Yoo , So Young Yoo , Hyun Cheol Chung , Ki Chang Keum , Won Min Yoo , Ki Jun Jeong
- Priority: KR2001-0060826 20010928
- Main IPC: C07K14/535
- IPC: C07K14/535 ; C12Q1/68 ; C40B30/04 ; C07H21/04
Abstract:
Disclosed are a method, a composition, a microarray, an antibody and a kit for diagnosis and prognosis of cancer, based on detection of deletion of the exon 3 region of G-CSF gene or levels of a mutated G-CSF protein having a deletion of an amino acid sequence corresponding to the exon 3 region, wherein the deletion of the exon 3 region of the G-CSF gene is used as a cancer biomarker.
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