Invention Application
![PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS](/docs/US/2012-12-20/US20120322791A1/abs.jpg.600x600.jpg)
- Patent Title: PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS
- Patent Title (中): 吡咯并[1,5-a]吡嗪化合物作为mTOR抑制剂
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Application No.: US13520274Application Date: 2011-01-18
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Publication No.: US20120322791A1Publication Date: 2012-12-20
- Inventor: M. Arshad Siddiqui , Yang Nan , Mehul F. Patel , Panduranga Adulla P. Reddy , Umar Faruk Mansoor , Zhaoyang Meng , Lalanthi Dilrukshi Vitharana , Lianyun Zhao , Amit K. Mandal , Duan Liu , Shuyi Tang , Andrew McRiner , David B. Belanger , Patrick J. Curran , Chaoyang Dai , Angie R. Angeles , Liping Yang , Matthew Hersh Daniels
- Applicant: M. Arshad Siddiqui , Yang Nan , Mehul F. Patel , Panduranga Adulla P. Reddy , Umar Faruk Mansoor , Zhaoyang Meng , Lalanthi Dilrukshi Vitharana , Lianyun Zhao , Amit K. Mandal , Duan Liu , Shuyi Tang , Andrew McRiner , David B. Belanger , Patrick J. Curran , Chaoyang Dai , Angie R. Angeles , Liping Yang , Matthew Hersh Daniels
- International Application: PCT/US11/21534 WO 20110118
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/5377 ; C07D487/08 ; A61K31/55 ; A61P35/00 ; C07D498/08 ; A61K31/5386 ; C07D513/08 ; A61K31/547 ; C07D491/147 ; C07D487/04 ; C07D471/08
![PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS](/abs-image/US/2012/12/20/US20120322791A1/abs.jpg.150x150.jpg)
Abstract:
The present invention provides Pyrazolopyrimidine Compounds of Formula (I): wherein L, T, Z, U, V, W, R3, R6, R7, R8, and m are as defined herein, and pharmaceutically acceptable salts of such Pyrazolopyrimidine Compounds. The Pyrazolopyrimidine Compounds are useful in the treatment of cancer and other diseases or disorders wherein mTOR is deregulated.
Public/Granted literature
- US09227971B2 Pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors Public/Granted day:2016-01-05
Information query
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