发明申请
US20120329808A1 DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
有权
DIHYDROTHIENO PYRIMIDINES作为AKT蛋白激酶抑制剂
- 专利标题： DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
- 专利标题（中）： DIHYDROTHIENO PYRIMIDINES作为AKT蛋白激酶抑制剂
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申请号： US12307526申请日： 2007-07-05
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公开(公告)号： US20120329808A1公开(公告)日： 2012-12-27
- 发明人: Ian S. Mitchell , James F. Blake , Rui Xu , Nicholas C. Kallan , Dengming Xiao , Keith Lee Spencer , Josef R. Bencsik
- 申请人： Ian S. Mitchell , James F. Blake , Rui Xu , Nicholas C. Kallan , Dengming Xiao , Keith Lee Spencer , Josef R. Bencsik
- 申请人地址： US CO Boulder
- 专利权人： Array Biopharma Inc.
- 当前专利权人： Array Biopharma Inc.
- 当前专利权人地址： US CO Boulder
- 国际申请： PCT/US07/72884 WO 20070705
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61P29/00 ; A61P15/02 ; A61P9/00 ; A61P25/28 ; A61P17/00 ; C07D495/04 ; A61P35/00
摘要：
The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
公开/授权文献
- US09303040B2 Substituted piperazines as AKT inhibitors 公开/授权日：2016-04-05
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