发明申请
- 专利标题: ANTIBODIES TO TUMOR ASSOCIATED PROTEINS
- 专利标题(中): 肿瘤相关蛋白抗体
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申请号: US13620170申请日: 2012-09-14
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公开(公告)号: US20130090376A1公开(公告)日: 2013-04-11
- 发明人: Arthur B. Raitano , Karen Jane Meyrick Morrison , Wangmao Ge , Pia M. Challita-Eid , Aya Jakobovits
- 申请人: Arthur B. Raitano , Karen Jane Meyrick Morrison , Wangmao Ge , Pia M. Challita-Eid , Aya Jakobovits
- 申请人地址: US CA Santa Monica
- 专利权人: AGENSYS, INC.
- 当前专利权人: AGENSYS, INC.
- 当前专利权人地址: US CA Santa Monica
- 主分类号: C07K16/18
- IPC分类号: C07K16/18
摘要:
A novel gene 024P4C12 (also designated 24P4C12) and its encoded protein, and variants thereof, are described wherein 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 24P4C12 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 24P4C12 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 24P4C12 can be used in active or passive immunization.
公开/授权文献
- US08779111B2 Antibodies to tumor associated proteins 公开/授权日:2014-07-15
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