Invention Application
- Patent Title: METHODS OF IDENTIFYING INTERACTIONS BETWEEN GENOMIC LOCI
- Patent Title (中): 识别基因组位置之间相互作用的方法
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Application No.: US13121158Application Date: 2009-09-22
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Publication No.: US20130096009A1Publication Date: 2013-04-18
- Inventor: Job Dekker , Erez Lieberman , Nynke Van Berkum , Andreas Gnirke , Eric Lander , Chad Nusbaum , Louise Williams , Alexandre Melnikov , Georgia Giannoukos
- Applicant: Job Dekker , Erez Lieberman , Nynke Van Berkum , Andreas Gnirke , Eric Lander , Chad Nusbaum , Louise Williams , Alexandre Melnikov , Georgia Giannoukos
- Applicant Address: US MA Boston US MA Cambridge US MA Cambridge US MA Cambridge
- Assignee: University of Massachusetts,Whitehead Institute for Biomedical Research,Massachusetts Institute of Technology,President and Fellows of Harvard College
- Current Assignee: University of Massachusetts,Whitehead Institute for Biomedical Research,Massachusetts Institute of Technology,President and Fellows of Harvard College
- Current Assignee Address: US MA Boston US MA Cambridge US MA Cambridge US MA Cambridge
- International Application: PCT/US09/05249 WO 20090922
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci.
Public/Granted literature
- US09434985B2 Methods of identifying interactions between genomic loci Public/Granted day:2016-09-06
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