Invention Application
- Patent Title: IDENTIFICATION OF DNA FRAGMENTS AND STRUCTURAL VARIATIONS
- Patent Title (中): 鉴定DNA片段和结构变异
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Application No.: US13649966Application Date: 2012-10-11
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Publication No.: US20130096841A1Publication Date: 2013-04-18
- Inventor: Bahram Ghaffarzadeh Kermani , Radoje Drmanac , Oleg Alferov
- Applicant: Complete Genomics, Inc.
- Applicant Address: US CA Mountain View
- Assignee: Complete Genomics, Inc.
- Current Assignee: Complete Genomics, Inc.
- Current Assignee Address: US CA Mountain View
- Main IPC: G06F17/18
- IPC: G06F17/18

Abstract:
Various short reads can be grouped and identified as coming from a same long DNA fragment (e.g., by using wells with a relatively low-concentration of DNA). A histogram of the genomic coverage of a group of short reads can provide the edges of the corresponding long fragment (pulse). The knowledge of these pulses can provide an ability to determine the haploid genome and to identify structural variations.
Public/Granted literature
- US09514272B2 Identification of DNA fragments and structural variations Public/Granted day:2016-12-06
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