发明申请
- 专利标题: IDENTIFICATION OF DNA FRAGMENTS AND STRUCTURAL VARIATIONS
- 专利标题(中): 鉴定DNA片段和结构变异
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申请号: US13649966申请日: 2012-10-11
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公开(公告)号: US20130096841A1公开(公告)日: 2013-04-18
- 发明人: Bahram Ghaffarzadeh Kermani , Radoje Drmanac , Oleg Alferov
- 申请人: Complete Genomics, Inc.
- 申请人地址: US CA Mountain View
- 专利权人: Complete Genomics, Inc.
- 当前专利权人: Complete Genomics, Inc.
- 当前专利权人地址: US CA Mountain View
- 主分类号: G06F17/18
- IPC分类号: G06F17/18
摘要:
Various short reads can be grouped and identified as coming from a same long DNA fragment (e.g., by using wells with a relatively low-concentration of DNA). A histogram of the genomic coverage of a group of short reads can provide the edges of the corresponding long fragment (pulse). The knowledge of these pulses can provide an ability to determine the haploid genome and to identify structural variations.
公开/授权文献
- US09514272B2 Identification of DNA fragments and structural variations 公开/授权日:2016-12-06
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