Invention Application
- Patent Title: NOVEL TRPV3 MODULATORS
- Patent Title (中): 新型TRPV3调制器
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Application No.: US13658374Application Date: 2012-10-23
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Publication No.: US20130131036A1Publication Date: 2013-05-23
- Inventor: Erol K. Bayburt , Bruce Clapham , Phil B. Cox , Jerome F. Daanen , Michael J. Dart , Gregory A. Gfesser , Arthur Gomtsyan , Michael E. Kort , Philip R. Kym , Robert G. Schmidt , Eric A. Voight
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Priority: CNPCT/CN2011/001761 20111024
- Main IPC: A61K31/435
- IPC: A61K31/435 ; A61K31/444 ; C07D239/26 ; A61K31/505 ; C07D405/10 ; A61K31/4433 ; C07D405/06 ; A61K31/443 ; A61K31/4427 ; C07D213/72 ; C07D401/06 ; A61K31/4545 ; C07D215/14 ; A61K31/47 ; C07D221/04 ; A61K31/4439 ; A61K45/06 ; C07D213/30

Abstract:
Disclosed herein are modulators of TRPV3 of formula (II): wherein G1, X1, X2, X3, X4, X5, G2, Ra, Rb, and u are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.
Public/Granted literature
- US08772500B2 TRPV3 modulators Public/Granted day:2014-07-08
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