发明申请
- 专利标题： COLON AND PANCREAS CANCER SPECIFIC ANTIGENS AND ANTIBODIES
- 专利标题（中）： 结肠癌和胰腺癌特异性抗原和抗体
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申请号： US13806200申请日： 2011-06-22
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公开(公告)号： US20130189268A1公开(公告)日： 2013-07-25
- 发明人: Xiulian Du , Janos Luka , Lewis Joe Stafford , Mark Semenuk , Xue-Ping Wang , Judith Kantor , Andrew J. Bristol
- 申请人： Xiulian Du , Janos Luka , Lewis Joe Stafford , Mark Semenuk , Xue-Ping Wang , Judith Kantor , Andrew J. Bristol
- 申请人地址： US MD Rockville
- 专利权人： Precision Biologics, Inc.
- 当前专利权人： Precision Biologics, Inc.
- 当前专利权人地址： US MD Rockville
- 国际申请： PCT/US2011/041502 WO 20110622
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C07K7/08
摘要：
This invention relates to NPC-1 antigen on the MUC5AC protein and 16C3 antigen on CEACAM5 and CEACAM6 proteins, and 31.1 epitope on the A33 protein are differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer, and colon cancer, and diagnostic and therapeutic usages. Further, NPC-1, 16C3, and/or 31.1 epitope specific antibodies and diagnostic and therapeutic methods of use.