发明申请
US20130190370A1 Novel Tetrahydronaphalene Antagonists to the Thromboxane A2 (TP) Receptor
审中-公开
新型四氢萘并呋喃对血栓素A2（TP）受体的拮抗剂
- 专利标题： Novel Tetrahydronaphalene Antagonists to the Thromboxane A2 (TP) Receptor
- 专利标题（中）： 新型四氢萘并呋喃对血栓素A2（TP）受体的拮抗剂
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申请号： US13812793申请日： 2011-07-27
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公开(公告)号： US20130190370A1公开(公告)日： 2013-07-25
- 发明人: John Q. Trojanowski , Virginia M.Y. Lee , Kurt R. Brunden , Amos B. Smith , Donna M. Huryn , Carlo Ballatore , Anne-Marie Hogan , Francesco Piscitelli
- 申请人： John Q. Trojanowski , Virginia M.Y. Lee , Kurt R. Brunden , Amos B. Smith , Donna M. Huryn , Carlo Ballatore , Anne-Marie Hogan , Francesco Piscitelli
- 申请人地址： US PA Philadephia
- 专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人： The Trustees of the University of Pennsylvania
- 当前专利权人地址： US PA Philadephia
- 国际申请： PCT/US11/45565 WO 20110727
- 主分类号： C07C311/20
- IPC分类号： C07C311/20 ; C07D317/28 ; A61K31/196 ; A61K45/06 ; A61K31/18 ; A61K31/41 ; A61K31/357 ; C07D257/04 ; A61K31/216
摘要：
The present invention relates to TP receptor antagonists, which have the ability to bind to TP receptor and optionally cross the blood brain barrier. The invention also provides compositions and methods for treating a disorder wherein activation of TP receptor is detrimental.
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