A method for climate control in buildings 1, having a ventilation system 2 with at least a control and regulation unit 6 and an air-guide unit, wherein the ventilation system 2 generates, by means of a separate building opening 10, at least one regulated inflow stream 4 which flows into the building 1 and/or at least one regulated outflow stream 5 which flows out of the building. The insulation and structure of the building 1 should be kept free of condensate. To this end, provision is made for at least one current value for a temperature Ti and/or a corresponding absolute internal atmospheric moisture level ∫il and/or a relative atmospheric moisture level φi or a partial steam pressure Wi in the interior of the building 1 and at least one current value for a temperature Ta and/or a corresponding absolute external atmospheric moisture level ∫al and/or a relative atmospheric moisture level φa or a partial steam pressure Wa outside the building 1 to be ascertained. The respectively measured values are supplied to the control and regulation unit 6. An overpressure or an underpressure or no pressure is generated by the air-guide unit in the building 1 as a function of the magnitude of the difference between the values.