- 专利标题: BENZIMIDAZOLE-CARBOXAMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS
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申请号: US13742783申请日: 2013-01-16
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公开(公告)号: US20130273568A1公开(公告)日: 2013-10-17
- 发明人: Robert Murray McKinnell , Roland Gendron , Lan Jiang , Seok-Ki Choi , Daniel D. Long , Paul R. Fatheree , Daniel Marquess
- 申请人: Robert Murray McKinnell , Roland Gendron , Lan Jiang , Seok-Ki Choi , Daniel D. Long , Paul R. Fatheree , Daniel Marquess
- 申请人地址: US CA South San Francisco
- 专利权人: THERAVANCE, INC.
- 当前专利权人: THERAVANCE, INC.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: G01N33/50
- IPC分类号: G01N33/50
摘要:
The invention relates to benzimidazole-carboxamide 5-HT4 receptor agonist compounds of formula (I) wherein R1 and X are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
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