- 专利标题： AZAINDAZOLE COMPOUNDS AND METHODS OF USE
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申请号： US13774938申请日： 2013-02-22
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公开(公告)号： US20130338157A1公开(公告)日： 2013-12-19
- 发明人: Penglie Zhang , Andrew M.K. Pennell , John J. Kim Wright , Wei Chen , Manmohan R. Leleti , Yandong Li , Lianfa Li , Yuan Xu , Mark M. Gleason , Yibin Zeng , Kevin Lloyd Greenman
- 申请人： Penglie Zhang , Andrew M.K. Pennell , John J. Kim Wright , Wei Chen , Manmohan R. Leleti , Yandong Li , Lianfa Li , Yuan Xu , Mark M. Gleason , Yibin Zeng , Kevin Lloyd Greenman
- 申请人地址： US CA Mountain View
- 专利权人： Chemocentryx, Inc.
- 当前专利权人： Chemocentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D487/04
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US09296740B2 Azaindazole compounds and methods of use 公开/授权日：2016-03-29
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