Invention Application
US20140080756A1 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5]NONANE DERIVATIVES
审中-公开
2,3-二氢-1H-吲哚-1-基] -2,7-二氮杂萘[3.5] NONANE衍生物
![2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5]NONANE DERIVATIVES](/docs/US/2014-03-20/US20140080756A1/abs.jpg.600x600.jpg)
- Patent Title: 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5]NONANE DERIVATIVES
- Patent Title (中): 2,3-二氢-1H-吲哚-1-基] -2,7-二氮杂萘[3.5] NONANE衍生物
-
Application No.: US14083275Application Date: 2013-11-18
-
Publication No.: US20140080756A1Publication Date: 2014-03-20
- Inventor: Samit K. Bhattacharya , Kimberly O. Cameron , Dilinie P. Fernando , Kim F. McClure , Daniel W. Kung , Allyn T. Londregan , Suvi T.M. Orr
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Main IPC: C07D471/10
- IPC: C07D471/10 ; A61K31/506 ; A61K31/53 ; A61K31/435 ; A61K31/497 ; C07D491/056 ; C07D513/04 ; A61K45/06
![2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5]NONANE DERIVATIVES](/abs-image/US/2014/03/20/US20140080756A1/abs.jpg.150x150.jpg)
Abstract:
The present invention provides a compound of Formula (I) a pharmaceutically salt thereof wherein R1, R2, Ra, L, Z, Z1 and Z2 are as defined herein, that act as Ghrelin antagonists or inverse agonists; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by the antagonism of the Ghrelin receptor.
Information query
