Invention Application
US20140099333A1 PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS
有权
吡咯烷酮衍生物作为GPR119调节剂用于治疗糖尿病，肥胖，DYSLIPIDEMIA和相关疾病
- Patent Title: PYRROLIDINONE DERIVATIVES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS
- Patent Title (中): 吡咯烷酮衍生物作为GPR119调节剂用于治疗糖尿病，肥胖，DYSLIPIDEMIA和相关疾病
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Application No.: US14048425Application Date: 2013-10-08
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Publication No.: US20140099333A1Publication Date: 2014-04-10
- Inventor: Lothar SCHWINK , Martin BOSSART , Heiner GLOMBIK , Matthias GOSSEL , Dieter KADEREIT , Thomas KLABUNDE , Thomas MAIER , Siegfried STENGELIN
- Applicant: Lothar SCHWINK , Martin BOSSART , Heiner GLOMBIK , Matthias GOSSEL , Dieter KADEREIT , Thomas KLABUNDE , Thomas MAIER , Siegfried STENGELIN
- Applicant Address: FR Paris
- Assignee: SANOFI
- Current Assignee: SANOFI
- Current Assignee Address: FR Paris
- Priority: EP12306231.7 20121009
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/4015 ; C07D401/12 ; A61K31/4439 ; A61K31/4545 ; C07D405/14 ; C07D401/14 ; A61K31/444 ; C07D413/14 ; A61K45/06 ; C07D207/12 ; C07D417/14
Abstract:
The present invention relates to pyrrolidinone derivatives. The pyrrolidinone derivatives are GPR119 modulators and useful for the prevention and/or treatment of diabetes, obesity, dyslipidemia and related disorders. The invention furthermore relates to the use of pyrrolidinone derivatives as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
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