Invention Application
- Patent Title: Azaquinazoline Inhibitors of Atypical Protein Kinase C
- Patent Title (中): Azaquinazoline非典型蛋白激酶C抑制剂
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Application No.: US14038915Application Date: 2013-09-27
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Publication No.: US20140113882A1Publication Date: 2014-04-24
- Inventor: Henry J. Breslin , Bruce D. Dorsey , Benjamin J. Dugan , Katherine M. Fowler , Robert L. Hudkins , Eugen F. Mesaros , Nathaniel J.T. Monck , Emma L. Morris , Ikeoluwa Olowoye , Gregory R. Ott , Gregoire A. Pave , Jonathan R. Roffey , Christelle N. Soudy , Ming Tao , Craig A. Zificsak , Allison L. Zulli
- Applicant: Cancer Research Technology Limited , Cephalon, Inc.
- Applicant Address: GB London US PA Frazer
- Assignee: Cancer Research Technology Limited,Cephalon, Inc.
- Current Assignee: Cancer Research Technology Limited,Cephalon, Inc.
- Current Assignee Address: GB London US PA Frazer
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07F9/6584 ; C07D498/04 ; C07D493/08
Abstract:
The present application provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. This application further describes compositions comprising the same. Compounds of formula (I) and their salts have aPKC inhibitory activity, and may be used to treat proliferative disorders.
Public/Granted literature
- US09914730B2 Azaquinazoline inhibitors of Atypical protein Kinase C Public/Granted day:2018-03-13
Information query
