发明申请
US20140113957A1 Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes
有权
抑制载脂蛋白C-III(APOC3)基因表达的组成和方法
- 专利标题: Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes
- 专利标题(中): 抑制载脂蛋白C-III(APOC3)基因表达的组成和方法
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申请号: US14125567申请日: 2012-06-21
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公开(公告)号: US20140113957A1公开(公告)日: 2014-04-24
- 发明人: Brian Bettencourt , Kevin Fitzgerald , Stuart Milstein , Martin Maier , Klaus Charisse , Rajeev Kallanthottathil , Satyanarayana Kuchimanchi , Muthiah Manoharan , Tuyen Nguyen
- 申请人: Brian Bettencourt , Kevin Fitzgerald , Stuart Milstein , Martin Maier , Klaus Charisse , Rajeev Kallanthottathil , Satyanarayana Kuchimanchi , Muthiah Manoharan , Tuyen Nguyen
- 国际申请: PCT/US2012/043642 WO 20120621
- 主分类号: C12N15/113
- IPC分类号: C12N15/113
摘要:
The invention relates to double-stranded ribonucleic acid (dsRNA) targeting an APOC3 gene, and methods of using the dsRNA to inhibit expression of APOC3.