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1.Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes 有权
Title translation: 抑制载脂蛋白C-III(APOC3)基因表达的组成和方法公开(公告)号:US20140113957A1
公开(公告)日:2014-04-24
申请号:US14125567
申请日:2012-06-21
Applicant: Brian Bettencourt , Kevin Fitzgerald , Stuart Milstein , Martin Maier , Klaus Charisse , Rajeev Kallanthottathil , Satyanarayana Kuchimanchi , Muthiah Manoharan , Tuyen Nguyen
Inventor: Brian Bettencourt , Kevin Fitzgerald , Stuart Milstein , Martin Maier , Klaus Charisse , Rajeev Kallanthottathil , Satyanarayana Kuchimanchi , Muthiah Manoharan , Tuyen Nguyen
IPC: C12N15/113
CPC classification number: C12N15/113 , C12N15/1137 , C12N2310/14 , C12N2310/315 , C12N2310/321 , C12N2310/344 , C12N2310/3515 , C12N2310/3521
Abstract: The invention relates to double-stranded ribonucleic acid (dsRNA) targeting an APOC3 gene, and methods of using the dsRNA to inhibit expression of APOC3.
Abstract translation: 本发明涉及靶向APOC3基因的双链核糖核酸(dsRNA),以及使用dsRNA抑制APOC3表达的方法。