An anti-vibration device for a vehicle has a first torque rod assembly having a first rod with one end fixed to an engine and the other end fixed to a vehicle body, an inertial mass supported on the first rod, and an actuator that reciprocates the inertial mass in an axial direction of the first rod, and a second torque rod assembly having a second rod with one end fixed to the engine and the other end fixed to a sub-frame that is installed on the vehicle body via an elastic member.