发明申请
US20140154220A1 Methods and Compositions for Improved Tissue Regeneration by Suppression of Interferon-Gamma and Tumor Necrosis Factor-Alpha
审中-公开
通过抑制干扰素 - γ和肿瘤坏死因子-α改善组织再生的方法和组合
- 专利标题： Methods and Compositions for Improved Tissue Regeneration by Suppression of Interferon-Gamma and Tumor Necrosis Factor-Alpha
- 专利标题（中）： 通过抑制干扰素 - γ和肿瘤坏死因子-α改善组织再生的方法和组合
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申请号： US14114070申请日： 2012-04-25
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公开(公告)号： US20140154220A1公开(公告)日： 2014-06-05
- 发明人: Songtao Shi , Yi Liu , Lei Wang
- 申请人： Songtao Shi , Yi Liu , Lei Wang
- 申请人地址： US CA Los Angels
- 专利权人： University of Southern Califonia
- 当前专利权人： University of Southern Califonia
- 当前专利权人地址： US CA Los Angels
- 国际申请： PCT/US12/35036 WO 20120425
- 主分类号： A61K35/28
- IPC分类号： A61K35/28 ; A61K31/616
摘要：
The present invention discloses methods, compositions and devices for improving tissue regeneration by suppressing the effects of several proinflammatory cytokines such as TNF-α and IFN-γ. Compositions and devices of this invention will generally include one or more anti-inflammatory agent(s) capable of reducing the level of TNF-α, IFN-γ, or both. Methods for improving tissue regeneration in accordance with this invention will generally have the step of applying a composition or device of the invention to a site in need of the composition or device. Also disclosed are methods for forming composition and devices of the invention and pharmaceutical compositions comprising one or more anti-inflammatory agent(s) effective of inhibiting or reducing the levels of TNF-α, IFN-γ, or both.
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