- 专利标题： High Fidelity Restriction Endonucleases
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申请号： US14137660申请日： 2013-12-20
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公开(公告)号： US20140154780A1公开(公告)日： 2014-06-05
- 发明人: Zhenyu Zhu , Aine Quimby , Shengxi Guan , Dapeng Sun , Yishu Huang , Xuhui Lai , Siu-hong Chan , Xianghui Li , Shuang-Yong Xu , Chunhua Zhang
- 申请人： New England Biolabs, Inc.
- 申请人地址： US MA Ipswich
- 专利权人： NEW ENGLAND BIOLABS, INC.
- 当前专利权人： NEW ENGLAND BIOLABS, INC.
- 当前专利权人地址： US MA Ipswich
- 主分类号： C12N9/22
- IPC分类号： C12N9/22 ; C12Q1/68
摘要：
Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.
公开/授权文献
- US09150901B2 High fidelity restriction endonucleases 公开/授权日：2015-10-06
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