发明申请
US20140199693A1 METHOD OF ANALYSING A BLOOD SAMPLE OF A SUBJECT FOR THE PRESENCE OF A DISEASE MARKER
审中-公开
分析疾病标志物存在的病人血液样本的方法
- 专利标题： METHOD OF ANALYSING A BLOOD SAMPLE OF A SUBJECT FOR THE PRESENCE OF A DISEASE MARKER
- 专利标题（中）： 分析疾病标志物存在的病人血液样本的方法
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申请号： US14006089申请日： 2012-01-16
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公开(公告)号： US20140199693A1公开(公告)日： 2014-07-17
- 发明人: Thomas Wurdinger , Rolf Jonas Nilsson
- 申请人： Thomas Wurdinger , Rolf Jonas Nilsson
- 申请人地址： NL Amsterdam
- 专利权人： STICHTING VU-VUMC
- 当前专利权人： STICHTING VU-VUMC
- 当前专利权人地址： NL Amsterdam
- 优先权： EP11158912.3 20110318; EP11167973.4 20110527; NLPCT/NL2011/050518 20110715
- 国际申请： PCT/NL2012/050025 WO 20120116
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention relates to a method of analysing a blood sample of a subject for the presence of a disease marker, said method comprising the steps of a) extracting nucleic acid from anucleated blood cells in said blood sample to provide an anucleated blood cells-extracted nucleic acid fraction, and b) analysing said anucleated blood cells-extracted nucleic acid fraction for the presence of a disease marker, wherein said disease marker is a disease-specific mutation in a gene of a cell of said subject, or wherein said disease marker is a disease-specific expression profile of genes of a cell of said subject.