发明申请
US20140227270A1 BISPECIFIC ANTI-CXCR7 IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
审中-公开
双功能抗CXCR7免疫球蛋白单变量域
- 专利标题： BISPECIFIC ANTI-CXCR7 IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
- 专利标题（中）： 双功能抗CXCR7免疫球蛋白单变量域
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申请号： US14008011申请日： 2012-03-28
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公开(公告)号： US20140227270A1公开(公告)日： 2014-08-14
- 发明人: Francis Descamps , David André Baptiste Maussang-Detaille , Maarten Van Roy , Regorius Leurs , Maria Gonzalez Pajuelo , Pascal Gerard Merchiers , Martine Smit , Catelijne Stortelers , Philippe Van Rompaey , Peter Vanlandschoot
- 申请人： Francis Descamps , David André Baptiste Maussang-Detaille , Maarten Van Roy , Regorius Leurs , Maria Gonzalez Pajuelo , Pascal Gerard Merchiers , Martine Smit , Catelijne Stortelers , Philippe Van Rompaey , Peter Vanlandschoot
- 国际申请： PCT/EP12/55499 WO 20120328
- 主分类号： C07K16/28
- IPC分类号： C07K16/28
摘要：
The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the present invention provides immunoglobulin single variable domains inhibiting CXCR7 mediated tumour growth.
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