- 专利标题: STABILISATION AND ISOLATION OF EXTRACELLULAR NUCLEIC ACIDS
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申请号: US14347051申请日: 2012-09-25
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公开(公告)号: US20140227688A1公开(公告)日: 2014-08-14
- 发明人: Martin Horlitz , Anabelle Schubert , Markus Sprenger-Haussels
- 申请人: Qiagen GmbH
- 申请人地址: DE Hilden
- 专利权人: Qiagen GmbH
- 当前专利权人: Qiagen GmbH
- 当前专利权人地址: DE Hilden
- 优先权: EP11182819.0 20110926
- 国际申请: PCT/EP2012/068892 WO 20120925
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention provides methods, compositions and devices for stabilizing the extracellular nucleic acid population in a cell-containing biological sample using an apoptosis inhibitor, preferably a caspase inhibitor, a hypertonic agent and/or a compound according to formula (1) as defined in the claims.
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