公开(公告)号：US20140227688A1

公开(公告)日：2014-08-14

申请号：US14347051

申请日：2012-09-25

申请人： Qiagen GmbH

发明人： Martin Horlitz ,  Anabelle Schubert ,  Markus Sprenger-Haussels

IPC分类号： C12Q1/68

CPC分类号： C12Q1/68 ,  C12N15/1003 ,  C12Q1/6806 ,  C12Q2527/125

摘要： The present invention provides methods, compositions and devices for stabilizing the extracellular nucleic acid population in a cell-containing biological sample using an apoptosis inhibitor, preferably a caspase inhibitor, a hypertonic agent and/or a compound according to formula (1) as defined in the claims.