发明申请
- 专利标题: CYCLOPROPANEAMINE COMPOUND
- 专利标题(中): 环丙烷胺化合物
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申请号: US14237440申请日: 2012-08-08
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公开(公告)号: US20140228405A1公开(公告)日: 2014-08-14
- 发明人: Naoki Tomita , Shigeo Kajii , Douglas Robert Cary , Daisuke Tomita , Shinichi Imamura , Ken Tsuchida , Satoru Matsuda , Ryujiro Hara
- 申请人: Naoki Tomita , Shigeo Kajii , Douglas Robert Cary , Daisuke Tomita , Shinichi Imamura , Ken Tsuchida , Satoru Matsuda , Ryujiro Hara
- 申请人地址: JP Osaka-shi, Osaka
- 专利权人: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 当前专利权人地址: JP Osaka-shi, Osaka
- 优先权: JP2011-174305 20110809
- 国际申请: PCT/JP2012/070267 WO 20120808
- 主分类号: C07C233/80
- IPC分类号: C07C233/80 ; C07D231/14 ; C07D335/02 ; C07D211/98
摘要:
The present invention provides a compound having a lysine-specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for cancer, and central nervous system diseases, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group or heterocyclic group optionally having substituent(s); R is H, a hydrocarbon group or heterocyclic group optionally having substituent(s); A and R are optionally bonded to each other to form a ring optionally having substituent(s); Q1, Q2, Q3 and Q4 are each a hydrogen atom or a substituent; Q1 and Q2, and Q3 and Q4, are each optionally bonded to each other to form a ring optionally having substituent(s); X is H, an acyclic hydrocarbon group or saturated cyclic group optionally having substituent(s); Y1, Y2 and Y3 are each H, a hydrocarbon group or heterocyclic group optionally having substituent(s); X and Y1, and Y1 and Y2, are each optionally bonded to each other to form a ring optionally having substituent(s); and Z1, Z2 and Z3 are each H or a substituent, or a salt thereof.
公开/授权文献
- US09278931B2 Cyclopropaneamine compound 公开/授权日:2016-03-08
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